Montreal doctors' breakthrough discovery about causes of cerebral palsy giving hope
A breakthrough discovery made by doctors at the Montreal Children's Hospital about the causes of certain forms of Cerebral Palsy (CP) is giving new hope to one West Island family.
Siena Zakaria is as smiley and playful as any 18-month-old, but at six months, her parents say they started noticing she wasn't hitting her milestones.
"She wasn't rolling. She wasn't able to support her head weight, sort of like a lack of focus," said her father, Nash Zakaria. "She wasn't able to concentrate on our voice."
Doctors determined that she has a form of CP, a developmental disorder that affects her movement.
"Cerebral Palsy is the most common cause of physical disability in childhood, and for the longest time, the prevalent belief was that it was caused by asphyxia at birth," said Dr. Maryam Oskoui, the head of neurology at the Montreal Children’s Hospital, and the co-author of a ground-breaking study that shows there’s more to the story.
"We looked to see if there was a genetic cause that could explain part of their clinical presentation," said Oskoui.
In many cases, including Siena's, a genetic mutation was actually the root cause of the disorder.
"It's always good to know," said her father. "It sort of gives you some sort of, I guess, relief. In the end, there's nothing that can be done about it for now, but we are hopeful that the future holds something positive for us."
Oskoui said the discovery could open the door to the development of new gene therapies, but there are also short-term benefits, as no two cases of the condition are the same.
"Cerebral Palsy is a spectrum disorder. Absolutely," said Oskoui. "If you've met one child with Cerebral Palsy, you've met the one child with Cerebral Palsy."
How the disorder is treated depends on the individual case and understanding the role genetics are playing will allow for better and more personalized care.
"This is where precision medicine is needed and an individualized approach to what really is impacting their daily life," said Oskoui.
Already, through physio and occupational therapy, Siena has gained a lot of strength.
"She's been able to hold her head much better than when she was younger with some minor support," said Zakaria. "She can sit up like this, but it's always supported with aid."
Her parents say it's comforting to know Siena's doctors are at the forefront of understanding her condition, but say it’s been a difficult journey so far.
"She's here, she's beautiful, she's happy, she's smiling," said her mother, Shana Meo. "It's the extra worry of not knowing: is she ever going to be able to walk? Is she ever going to be able to speak?"
"Nobody wants to think that their child isn't perfect," said Nash. "It has been difficult, but it will continue to be difficult. But family support system, friends, everybody has been there for us. We're very grateful. We're thankful. And as I said to us, she's perfect."
CTVNews.ca Top Stories
Liberal MP says she's leaving politics over disrespectful dialogue, threats, misogyny
Liberal MP Pam Damoff says she won't run again in the next federal election, saying she has experienced misogyny, disrespectful dialogue in politics and threats to her life.
Concerns about Plexiglass prompt inspections at some Loblaws locations in Ottawa
Inspections are underway at more than one Loblaws location in Ottawa after complaints were filed about tall Plexiglass barriers.
Federal employees will be required to spend 3 days a week in the office
Starting in September, public servants in the core public administration will be required to work in the office a minimum of three days a week. The Treasury Board Secretariat says executives will need to be in the office four days per week.
OPP officer said 'someone's going to get hurt' before wrong-way Hwy. 401 crash
As multiple Durham police cruisers were chasing a robbery suspect on the wrong side of Highway 401 Monday night, an Ontario Provincial Police officer shared his concerns, telling a dispatcher, "Someone's going to get hurt."
Ont. woman who faked pregnancy to defraud doulas arrested again on similar charges
Victims of a Brantford, Ont., woman who was sentenced to house arrest earlier this year for defrauding and deceiving doulas say they’re not surprised she’s been apprehended again on similar charges.
Five human skeletons, missing hands and feet, found outside house of Nazi leader Hermann Göring
Archeologists have unearthed the skeletons of five people, missing their hands and feet, at a former Nazi military base in Poland.
Poilievre returns to House unrepentant for calling Trudeau 'wacko,' Speaker not resigning
An unrepentant Pierre Poilievre returned to the House of Commons on Wednesday to pepper the prime minister about his drug decriminalization policies after being booted the day prior for refusing to take back calling Justin Trudeau 'wacko' over his approach to the issue.
Construction begins on LGBTQ2S+ national monument in Ottawa
Shovels have hit the ground for constuction on Canada's LGBTQ2S+ national monument in Ottawa.
B.C. man awarded $5,000 in damages in first-of-it-kind intimate image case
In a first-of-its-kind case, a B.C. tribunal has ruled on a dispute involving the non-consensual sharing of intimate images, awarding damages and issuing orders that the photos be destroyed and taken offline.