In a statement, Lalonde's agent wrote that the 75-year-old died in his Outremont home on Tuesday, surrounded by loved ones and family.
Lalonde revealed in 2010 that he had Parkinson's disease.
Lalonde hosted multiple TV programs on CFCF-12, including The Pierre Lalonde Show, Mad Dash, and the Telethon of Stars.
A bilingual icon, he also hosted French-language TV shows including "Jeunesse d'aujourd'hui" starting in 1962, and "Action Reaction" in 1986.
Born on Jan. 21, 1941, Lalonde began his singing career at the tender age of four, when he performed on CKAC radio's Cafe-Concert Kraft.
He went to school in the United States, then returned to Quebec in the 1960s where he quickly found work as a TV host.
Lalonde also recorded albums, including 1963's "En d'autres mots" which earned him a Gala award for newcomer of the year.
South of the border Lalonde adopted an Americanized pseudonym, Peter Martin, and released an English-language album and hosted a TV show.
In 2011 the National Assembly awarded Lalonde its medal of honour for his contribution to Quebec's artistic works.
Je me rappelle que pour la première campagne de pub d'Air Transat, on avait choisi "C'est le temps des vacances" https://t.co/iCJl40gEM9
— François Legault (@francoislegault) June 22, 2016